Proteins contain specific catalytic “domains” which perform the various function of the protein. For example, domains can be responsible for the protein interacting with and binding to DNA, or for holding onto a specific metal ion. We can identify these domains and their function from their amino acid sequence.
Translating DNA Puzzle
I found a table of protein domain sequences that will be helpful!
Table 1: Common Protein Catalytic Domain Sequences
Domain Function | Protein Sequence |
---|---|
Iron Binding | Ala-Cys-Ser |
Zinc Binding | Gly-Ser-Pro |
RNA Cutting | Ser-Pro-Ala-Gly |
DNA Cutting | Gly-Arg-Leu-His |
Nucleus Transport | Ala-Gly-Asp-Pro |
RNA Binding | Leu-Leu-Gln-His |
DNA Binding | Gly-Ser-Asn-Arg |
I’ve listed below the known functions from a selection of possible proteins that this sequence could belong to.
Protein 1:
-Has an Iron Binding Domain -Has a RNA Binding Domain -Has a DNA Cutting Domain
-Has an Iron Binding Domain -Has a RNA Binding Domain -Has a DNA Cutting Domain
Protein 2:
-Has a Zinc Binding Domain -Has a DNA Binding Domain -Has a RNA Cutting Domain
-Has a Zinc Binding Domain -Has a DNA Binding Domain -Has a RNA Cutting Domain
Protein 3:
-Has an Iron Binding Domain -Has a DNA Binding Domain -Has a Nucleus Transport Domain
-Has an Iron Binding Domain -Has a DNA Binding Domain -Has a Nucleus Transport Domain
Protein 4:
-Has a Zinc Binding Domain -Has a DNA Binding Domain -Has a DNA Cutting Domain
-Has a Zinc Binding Domain -Has a DNA Binding Domain -Has a DNA Cutting Domain
Protein 5:
-Has a RNA Binding Domain -Has a DNA Binding Domain -Has a DNA Cutting Domain
-Has a RNA Binding Domain -Has a DNA Binding Domain -Has a DNA Cutting Domain
Protein 6
-Has a RNA Binding Domain -Has a RNA Cutting Domain -Has a DNA Cutting Domain
-Has a RNA Binding Domain -Has a RNA Cutting Domain -Has a DNA Cutting Domain
Translating the DNA code confirmed the mystery protein was protein
Which protein does the sequenced DNA code for?