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Translating DNA Puzzle

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Clues and the answer will become available during the puzzle.


Clue 1

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Clue 2

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Answer

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Remember that DNA is read in 3 letter codons

Figure 1: DNA codon code
Figure 2: Sequencing Data: Sample 26112020_01

Sequencing data looks good!
Note: the new DNA extraction kit is working well

Proteins contain specific catalytic “domains” which perform the various function of the protein. For example, domains can be responsible for the protein interacting with and binding to DNA, or for holding onto a specific metal ion. We can identify these domains and their function from their amino acid sequence.

I found a table of protein domain sequences that will be helpful!

Table 1: Common Protein Catalytic Domain Sequences

Domain Function Protein Sequence
Iron Binding Ala-Cys-Ser
Zinc Binding Gly-Ser-Pro
RNA Cutting Ser-Pro-Ala-Gly
DNA Cutting Gly-Arg-Leu-His
Nucleus Transport Ala-Gly-Asp-Pro
RNA Binding Leu-Leu-Gln-His
DNA Binding Gly-Ser-Asn-Arg

I’ve listed below the known functions from a selection of possible proteins that this sequence could belong to.

Protein 1:
-Has an Iron Binding Domain -Has a RNA Binding Domain -Has a DNA Cutting Domain
Protein 2:
-Has a Zinc Binding Domain -Has a DNA Binding Domain -Has a RNA Cutting Domain
Protein 3:
-Has an Iron Binding Domain -Has a DNA Binding Domain -Has a Nucleus Transport Domain
Protein 4:
-Has a Zinc Binding Domain -Has a DNA Binding Domain -Has a DNA Cutting Domain
Protein 5:
-Has a RNA Binding Domain -Has a DNA Binding Domain -Has a DNA Cutting Domain
Protein 6
-Has a RNA Binding Domain -Has a RNA Cutting Domain -Has a DNA Cutting Domain

Translating the DNA code confirmed the mystery protein was protein

Which protein does the sequenced DNA code for?